Croote, D., Quake, S.R. Food allergen detection by mass spectrometry: the role of systems biology. npj Syst Biol Appl. 2016 Sep 29; 2:16022.
This rose plot enables visualization of proteotypic peptides. Each colored rose petal corresponds to a peptide and is bounded by thin gray petals, which represent tryptic cut sites. The radial magnitude of each peptide corresponds to the number of publications which report it.
Hover over a rose petal with your mouse to see the peptide. Click on a rose petal to see the species specificity of that peptide and add it to your cart.
MAKAFVFSLCLLLVFNGCLAARQSQLSPQNQCQLNQLQAREPDNRIQAEAGQIETWNFNQEDFQCAGVAASRITIQRNGLHLPSYSNAPQLIYIVQGRGVLGAVFSGCPETFEESQQSSQQGRQQEQEQERQQQQQGEQGRQQGQQEQQQERQGRQQGRQQQEEGRQQEQQQGQQGRPQQQQQFRQFDRHQKTRRIREGDVVAIPAGVAYWSYNDGDQELVAVNLFHVSSDHNQLDQNPRKFYLAGNPENEFNQQGQSQPRQQGEQGRPGQHQQPFGRPRQQEQQGSGNNVFSGFNTQLLAQALNVNEETARNLQGQNDNRNQIIRVRGNLDFVQPPRGRQEREHEERQQEQLQQERQQQGGQLMANGLEETFCSLRLKENIGNPERADIFSPRAGRISTLNSHNLPILRFLRLSAERGFFYRNGIYSPHWNVNAHSVVYVIRGNARVQVVNENGDAILDQEVQQGQLFIVPQNHGVIQQAGNQGFEYFAFKTEENAFINTLAGRTSFLRALPDEVLANAYQISREQARQLKYNRQETIALSSSQQRRAVV
UniProt: E3SH28 IUIS: Pru du 6Explore peptide targets for mass spectrometry by adjusting the selection criteria below. Results from empirical and computational prediction tools have been aggregated for convenience.
| 1 | Peptide | 2 | Exp.3 | ESP4 | CONSeQ5 |
|---|---|---|---|---|---|
| K | AFVFSLCLLLVFNGCLAAR | Q | 0 | 0.227 | 0.09992 |
| R | QSQLSPQNQCQLNQLQAR | E | 0 | 0.607 | 0.41646 |
| R | IQAEAGQIETWNFNQEDFQCAGVAASR | I | 0 | 0.345 | 0.13008 |
| R | NGLHLPSYSNAPQLIYIVQGR | G | 3 | 0.657 | 0.10488 |
| R | GVLGAVFSGCPETFEESQQSSQQGR | Q | 2 | 0.505 | 0.38044 |
| R | QQEQEQER | Q | 0 | 0.209 | 0.26778 |
| R | QQQQQGEQGR | Q | 0 | 0.263 | 0.27344 |
| R | QQGQQEQQQER | Q | 1 | 0.245 | 0.32678 |
| R | QQQEEGR | Q | 0 | 0.216 | 0.1398 |
| R | QQEQQQGQQGRPQQQQQFR | Q | 1 | 0.297 | 0.37798 |
| K | FYLAGNPENEFNQQGQSQPR | Q | 1 | 0.779 | 0.44558 |
| R | QQGEQGRPGQHQQPFGRPR | Q | 0 | 0.249 | 0.31648 |
| R | NLQGQNDNR | N | 1 | 0.286 | 0.20464 |
| R | GNLDFVQPPR | G | 6 | 0.642 | 0.77796 |
| R | QQEQLQQER | Q | 4 | 0.244 | 0.33544 |
| R | QQQGGQLMANGLEETFCSLR | L | 0 | 0.566 | 0.17606 |
| K | ENIGNPER | A | 0 | 0.211 | 0.19948 |
| R | ADIFSPR | A | 1 | 0.274 | 0.33404 |
| R | ISTLNSHNLPILR | F | 3 | 0.686 | 0.49374 |
| R | NGIYSPHWNVNAHSVVYVIR | G | 1 | 0.425 | 0.17336 |
| K | TEENAFINTLAGR | T | 3 | 0.709 | 0.87564 |
| R | ALPDEVLANAYQISR | E | 6 | 0.795 | 0.8587 |
| R | QETIALSSSQQR | R | 3 | 0.43 | 0.53732 |
| ^ | CLLLLFNGCLASR | Q | 0 | 0.42 | 0.25768 |
| R | QHIFGQNK | E | 0 | 0.281 | 0.2444 |
| K | EWQLNQLEAR | E | 0 | 0.406 | 0.4331 |
| R | TIEPNGLHLPSYVNAPQLIYIVR | G | 0 | 0.766 | 0.11022 |
| R | QEGGQGQQQFQGEDQQDR | H | 0 | 0.637 | 0.33556 |
| R | FYLAGNPQDEFNPQQQGR | Q | 1 | 0.81 | 0.4381 |
| R | NLQGQDDNR | N | 0 | 0.275 | 0.15902 |
| R | VQGQLDFVSPFSR | S | 1 | 0.803 | 0.74446 |
| R | QQEEQQSQR | E | 0 | 0.199 | 0.29186 |
| R | EQEQQGGGGQDNGVEETFCSAR | L | 0 | 0.567 | 0.43352 |
| R | LSQNIGDPSR | A | 1 | 0.444 | 0.75606 |
| R | ADFYNPQGGR | I | 2 | 0.484 | 0.41086 |
| R | NHLPILR | Y | 1 | 0.317 | 0.27074 |
| K | GVLYNNAIYTPHWHTNANALVYAIR | G | 0 | 0.351 | 0.0633 |
| R | VQVVNENGDPILDDEVR | E | 1 | 0.714 | 0.45464 |
| R | EGQLFLIPQNHAVITQASNEGFEYISFR | T | 0 | 0.373 | 0.03568 |
| R | TDENGFTNTLAGR | T | 2 | 0.659 | 0.7319 |
| R | ALPDEVLQNAFR | I | 1 | 0.812 | 0.85814 |
| R | LLSATSPPR | G | 2 | 0.401 | 0.71338 |
| R | LMSILGY | $ | 0 | 0.196 | 0.35906 |
1 Previous amino acid (^ = Start of protein)
2 Next amino acid ($ = End of protein)
3 Exp. = Number of publications in which this peptide has been reported experimentally
4 ESP = ESP Predictor. Fusaro VA, et al. Nat Botechnol 2009; 27(2): 190-198. doi
5 CONSeQ = CONSeQuence. Eyers CE, et al. Mol Cell Proteomics 2011; 10(11). doi
Underline: Peptide occurs within the first 20 amino acids from the start of the protein. Use caution as the protein may contain a cleaved signaling sequence.
Strike-through: Peptide is present in a protein from another allergen species and is thus nonspecific.