Croote, D., Quake, S.R. Food allergen detection by mass spectrometry: the role of systems biology. npj Syst Biol Appl. 2016 Sep 29; 2:16022.
This rose plot enables visualization of proteotypic peptides. Each colored rose petal corresponds to a peptide and is bounded by thin gray petals, which represent tryptic cut sites. The radial magnitude of each peptide corresponds to the number of publications which report it.
Hover over a rose petal with your mouse to see the peptide. Click on a rose petal to see the species specificity of that peptide and add it to your cart.
MSITKIHAREILDSRGNPTVEVDLYTAKGRFRAAVPSGASTGVHEALELRDGDKSRYLGKGTVKAVDHVNKDIAAKLIEKKFSVVDQEKIDHFMLELDGTENKSKFGANAILGVSLAVCKAGAAEKGVPLYRHIADLAGHKDVILPCPAFNVINGGSHAGNKLAMQEFMILPIGASNFHEAMRIGAEVYHNLKNVIKAKYGKDATNVGDEGGFAPNILENNEALELLKTAIEKAGYPDKIIIGMDVAASEFYKAGKYDLDFKSPDDPARYITGDQLGDLYKSFIKGYPVQSIEDPFDQDDWAAWTKFTAAVDIQVVGDDLTVTNPKRIQQAVEKKACNCLLLKVNQIGSVTESIKACKLAQSNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEELGAKAKFAGKDYRHPKIN
UniProt: B5DGQ7 IUIS: Sal s 2Explore peptide targets for mass spectrometry by adjusting the selection criteria below. Results from empirical and computational prediction tools have been aggregated for convenience.
1 | Peptide | 2 | Exp.3 | ESP4 | CONSeQ5 |
---|---|---|---|---|---|
R | GNPTVEVDLYTAK | G | 0 | 0.763 | 0.96596 |
R | AAVPSGASTGVHEALELR | D | 0 | 0.809 | 0.74794 |
K | AVDHVNK | D | 0 | 0.245 | 0.07922 |
K | FSVVDQEK | I | 0 | 0.285 | 0.51634 |
K | IDHFMLELDGTENK | S | 0 | 0.675 | 0.37082 |
K | FGANAILGVSLAVCK | A | 0 | 0.52 | 0.32592 |
R | HIADLAGHK | D | 0 | 0.392 | 0.27984 |
K | DVILPCPAFNVINGGSHAGNK | L | 0 | 0.806 | 0.27504 |
K | LAMQEFMILPIGASNFHEAMR | I | 0 | 0.455 | 0.04188 |
R | IGAEVYHNLK | N | 0 | 0.558 | 0.41744 |
K | DATNVGDEGGFAPNILENNEALELLK | T | 0 | 0.658 | 0.20402 |
K | IIIGMDVAASEFYK | A | 0 | 0.482 | 0.14076 |
K | SPDDPAR | Y | 0 | 0.117 | 0.0977 |
R | YITGDQLGDLYK | S | 0 | 0.568 | 0.44876 |
K | GYPVQSIEDPFDQDDWAAWTK | F | 0 | 0.655 | 0.20918 |
K | FTAAVDIQVVGDDLTVTNPK | R | 0 | 0.798 | 0.07246 |
R | IQQAVEK | K | 0 | 0.223 | 0.16412 |
K | ACNCLLLK | V | 0 | 0.294 | 0.40778 |
K | VNQIGSVTESIK | A | 0 | 0.576 | 0.88786 |
K | LAQSNGWGVMVSHR | S | 0 | 0.519 | 0.4508 |
R | SGETEDTFIADLVVGLCTGQIK | T | 0 | 0.549 | 0.03902 |
R | IEEELGAK | A | 0 | 0.236 | 0.50324 |
1 Previous amino acid (^ = Start of protein)
2 Next amino acid ($ = End of protein)
3 Exp. = Number of publications in which this peptide has been reported experimentally
4 ESP = ESP Predictor. Fusaro VA, et al. Nat Botechnol 2009; 27(2): 190-198. doi
5 CONSeQ = CONSeQuence. Eyers CE, et al. Mol Cell Proteomics 2011; 10(11). doi
Underline: Peptide occurs within the first 20 amino acids from the start of the protein. Use caution as the protein may contain a cleaved signaling sequence.
Strike-through: Peptide is present in a protein from another allergen species and is thus nonspecific.