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Croote, D., Quake, S.R. Food allergen detection by mass spectrometry: the role of systems biology. npj Syst Biol Appl. 2016 Sep 29; 2:16022.

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Atlantic-salmon Protein: Sal s 3 | Aldolase A

Empirical Proteotypic Peptide Explorer:

This rose plot enables visualization of proteotypic peptides. Each colored rose petal corresponds to a peptide and is bounded by thin gray petals, which represent tryptic cut sites. The radial magnitude of each peptide corresponds to the number of publications which report it.

Hover over a rose petal with your mouse to see the peptide. Click on a rose petal to see the species specificity of that peptide and add it to your cart.


Sequence - 363 amino acids

MPHAFPFLTPDQKKELSDIALKIVAKGKGILAADESTGSVAKRFQSINTENTEENRRLYRQLLFTADDRAGPCIGGVIFFHETLYQKTDAGKTFPEHVKSRGWVVGIKVDKGVVPLAGTNGETTTQGLDGLYERCAQYKKDGCDFAKWRCVLKITSTTPSRLAIMENCNVLARYASICQMHGIVPIVEPEILPDGDHDLKRTQYVTEKVLAAMYKALSDHHVYLEGTLLKPNMVTAGHSCSHKYTHQEIAMATVTALRRTVPPAVPGVTFLSGGQSEEEASINLNVMNQCPLHRPWALTFSYGRALQASALKAWGGKPGNGKAAQEEFIKRALANSLACQGKYVASGDSAAAGDSLFVANHAY

UniProt: B5DGM7   IUIS: Sal s 3

Peptide Selector Tool

Explore peptide targets for mass spectrometry by adjusting the selection criteria below. Results from empirical and computational prediction tools have been aggregated for convenience.

Exclude:
Peptide Characteristics:

Minimum length:

Maximum length:

1Peptide2Exp.3ESP4CONSeQ5
^ MPHAFPFLTPDQK K 0 0.574 0.41644
K ELSDIALK I 0 0.298 0.63736
K GILAADESTGSVAK R 0 0.638 0.84746
R FQSINTENTEENR R 0 0.539 0.44328
R QLLFTADDR A 0 0.485 0.65378
R AGPCIGGVIFFHETLYQK T 0 0.64 0.07994
K TFPEHVK S 0 0.24 0.20698
R GWVVGIK V 0 0.217 0.5208
K GVVPLAGTNGETTTQGLDGLYER C 0 0.701 0.28574
K DGCDFAK W 0 0.221 0.1395
K ITSTTPSR L 0 0.253 0.29368
R LAIMENCNVLAR Y 0 0.498 0.34422
R YASICQMHGIVPIVEPEILPDGDHDLK R 0 0.638 0.13814
R TQYVTEK V 0 0.227 0.13532
K VLAAMYK A 0 0.215 0.29004
K ALSDHHVYLEGTLLKPNMVTAGHSCSHK Y 0 0.257 0.12982
K YTHQEIAMATVTALR R 0 0.538 0.3203
R ALQASALK A 0 0.262 0.39142
K AWGGKPGNGK A 0 0.218 0.20776
K AAQEEFIK R 0 0.261 0.52292
R ALANSLACQGK Y 0 0.387 0.6248
K YVASGDSAAAGDSLFVANHAY $ 0 0.521 0.17568

1 Previous amino acid (^ = Start of protein)

2 Next amino acid ($ = End of protein)

3 Exp. = Number of publications in which this peptide has been reported experimentally

4 ESP = ESP Predictor. Fusaro VA, et al. Nat Botechnol 2009; 27(2): 190-198. doi

5 CONSeQ = CONSeQuence. Eyers CE, et al. Mol Cell Proteomics 2011; 10(11). doi

Underline: Peptide occurs within the first 20 amino acids from the start of the protein. Use caution as the protein may contain a cleaved signaling sequence.

Strike-through: Peptide is present in a protein from another allergen species and is thus nonspecific.

 

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