Croote, D., Quake, S.R. Food allergen detection by mass spectrometry: the role of systems biology. npj Syst Biol Appl. 2016 Sep 29; 2:16022.
This rose plot enables visualization of proteotypic peptides. Each colored rose petal corresponds to a peptide and is bounded by thin gray petals, which represent tryptic cut sites. The radial magnitude of each peptide corresponds to the number of publications which report it.
Hover over a rose petal with your mouse to see the peptide. Click on a rose petal to see the species specificity of that peptide and add it to your cart.
MDAIKKKMQAMKLEKDNAMDRADTLEQQNKEANNRAEKSEEEVHNLQKRMQQLENDLDQVQESLLKANIQLVEKDKALSNAEGEVAALNRRIQLLEEDLERSEERLNTATTKLAEASQAADESERMRKVLENRSLSDEERMDALENQLKEARFLAEEADRKYDEVARKLAMVEADLERAEERAETGESKIVELEEELRVVGNNLKSLEVSEEKANQREEAYKEQIKTLTNKLKAAEARAEFAERSVQKLQKEVDRLEDELVNEKEKYKSITDELDQTFSELSGY
UniProt: A1KYZ2 IUIS: Pen m 1Explore peptide targets for mass spectrometry by adjusting the selection criteria below. Results from empirical and computational prediction tools have been aggregated for convenience.
| 1 | Peptide | 2 | Exp.3 | ESP4 | CONSeQ5 |
|---|---|---|---|---|---|
| R | ADTLEQQNK | E | 1 | 0.256 | 0.23162 |
| K | SEEEVHNLQK | R | 1 | 0.358 | 0.26946 |
| R | MQQLENDLDQVQESLLK | A | 1 | 0.637 | 0.3154 |
| K | ANIQLVEK | D | 1 | 0.281 | 0.6087 |
| K | ALSNAEGEVAALNR | R | 2 | 0.675 | 0.83692 |
| R | IQLLEEDLER | S | 0 | 0.515 | 0.59988 |
| R | LNTATTK | L | 0 | 0.228 | 0.07776 |
| K | LAEASQAADESER | M | 1 | 0.449 | 0.41992 |
| R | SLSDEER | M | 0 | 0.212 | 0.05738 |
| R | MDALENQLK | E | 1 | 0.274 | 0.62192 |
| R | FLAEEADR | K | 2 | 0.316 | 0.60278 |
| K | LAMVEADLER | A | 1 | 0.437 | 0.63148 |
| R | AETGESK | I | 0 | 0.18 | 0.01362 |
| K | IVELEEELR | V | 2 | 0.364 | 0.5101 |
| R | VVGNNLK | S | 0 | 0.238 | 0.24084 |
| K | SLEVSEEK | A | 0 | 0.213 | 0.3842 |
| R | LEDELVNEK | E | 0 | 0.374 | 0.50822 |
| K | SITDELDQTFSELSGY | $ | 1 | 0.42 | 0.34748 |
1 Previous amino acid (^ = Start of protein)
2 Next amino acid ($ = End of protein)
3 Exp. = Number of publications in which this peptide has been reported experimentally
4 ESP = ESP Predictor. Fusaro VA, et al. Nat Botechnol 2009; 27(2): 190-198. doi
5 CONSeQ = CONSeQuence. Eyers CE, et al. Mol Cell Proteomics 2011; 10(11). doi
Underline: Peptide occurs within the first 20 amino acids from the start of the protein. Use caution as the protein may contain a cleaved signaling sequence.
Strike-through: Peptide is present in a protein from another allergen species and is thus nonspecific.