Croote, D., Quake, S.R. Food allergen detection by mass spectrometry: the role of systems biology. npj Syst Biol Appl. 2016 Sep 29; 2:16022.
This rose plot enables visualization of proteotypic peptides. Each colored rose petal corresponds to a peptide and is bounded by thin gray petals, which represent tryptic cut sites. The radial magnitude of each peptide corresponds to the number of publications which report it.
Hover over a rose petal with your mouse to see the peptide. Click on a rose petal to see the species specificity of that peptide and add it to your cart.
MAKLFLLSLGIFLLFHCCLAIEYEQEELYECRIQRLTAQEPQYRLEAEAGVSEVWDYTDQQFRCAGVAALRNTIRPQGLLLPVYTNAPKLYYVTQGRGILGVLMPGCPETFQSMSQFQGSREQEEERGRFQDQHQKVHHLKKGDIIAIPAGVALWCYNDGDEDLVTVLVQHTASDLNQLDQNPRHFFLAGNIQRSQKQRGERYGLRGGQQILADNVFKGFNMEALADVLGFGMDTETARKVRGEDDQRGHIVRVEQGLKVIRPPRIREELEQQEGGGYNGLEETICSATFIQNIDNPAEADFYNPRAGRLTTVNSLKVPILTFLQLSAMKGVLYENAMMAPLWRLNANSVVYAVRGEARVQIVDHRGETVFDDNLREGQMVVVPQNFVVVKQAGSRGFEWVVFNTNDNALFSTAAGRTSPLRGIPVGVLANAYRLSQEEARRIKLNRDEAVLFQPGSRSRGRASA
UniProt: Q84ND2 IUIS: Ber e 2Explore peptide targets for mass spectrometry by adjusting the selection criteria below. Results from empirical and computational prediction tools have been aggregated for convenience.
| 1 | Peptide | 2 | Exp.3 | ESP4 | CONSeQ5 |
|---|---|---|---|---|---|
| K | LFLLSLGIFLLFHCCLAIEYEQEELYECR | I | 0 | 0.163 | 0.05096 |
| R | LTAQEPQYR | L | 0 | 0.366 | 0.54848 |
| R | LEAEAGVSEVWDYTDQQFR | C | 0 | 0.481 | 0.12204 |
| R | CAGVAALR | N | 0 | 0.29 | 0.48994 |
| R | NTIRPQGLLLPVYTNAPK | L | 0 | 0.578 | 0.40726 |
| K | LYYVTQGR | G | 0 | 0.292 | 0.39396 |
| R | GILGVLMPGCPETFQSMSQFQGSR | E | 0 | 0.517 | 0.0861 |
| R | FQDQHQK | V | 0 | 0.207 | 0.13406 |
| R | HFFLAGNIQR | S | 0 | 0.575 | 0.18694 |
| R | GGQQILADNVFK | G | 0 | 0.605 | 0.78042 |
| K | GFNMEALADVLGFGMDTETAR | K | 0 | 0.552 | 0.04786 |
| R | LTTVNSLK | V | 0 | 0.281 | 0.54272 |
| K | VPILTFLQLSAMK | G | 0 | 0.538 | 0.17198 |
| K | GVLYENAMMAPLWR | L | 0 | 0.524 | 0.13704 |
| R | LNANSVVYAVR | G | 0 | 0.532 | 0.68356 |
| R | VQIVDHR | G | 0 | 0.246 | 0.29134 |
| R | GETVFDDNLR | E | 0 | 0.58 | 0.69166 |
| R | EGQMVVVPQNFVVVK | Q | 0 | 0.541 | 0.43384 |
| R | GFEWVVFNTNDNALFSTAAGR | T | 0 | 0.46 | 0.04266 |
| R | GIPVGVLANAYR | L | 0 | 0.66 | 0.83882 |
| R | LSQEEAR | R | 0 | 0.232 | 0.14388 |
| R | DEAVLFQPGSR | S | 0 | 0.694 | 0.9645 |
1 Previous amino acid (^ = Start of protein)
2 Next amino acid ($ = End of protein)
3 Exp. = Number of publications in which this peptide has been reported experimentally
4 ESP = ESP Predictor. Fusaro VA, et al. Nat Botechnol 2009; 27(2): 190-198. doi
5 CONSeQ = CONSeQuence. Eyers CE, et al. Mol Cell Proteomics 2011; 10(11). doi
Underline: Peptide occurs within the first 20 amino acids from the start of the protein. Use caution as the protein may contain a cleaved signaling sequence.
Strike-through: Peptide is present in a protein from another allergen species and is thus nonspecific.