Croote, D., Quake, S.R. Food allergen detection by mass spectrometry: the role of systems biology. npj Syst Biol Appl. 2016 Sep 29; 2:16022.
This rose plot enables visualization of proteotypic peptides. Each colored rose petal corresponds to a peptide and is bounded by thin gray petals, which represent tryptic cut sites. The radial magnitude of each peptide corresponds to the number of publications which report it.
Hover over a rose petal with your mouse to see the peptide. Click on a rose petal to see the species specificity of that peptide and add it to your cart.
MGPPTKFSFSLFLVSVLVLCLGFALAKIDPELKQCKHQCKVQRQYDEQQKEQCVKECEKYYKEKKGREREHEEEEEEWGTGGVDEPSTHEPAEKHLSQCMRQCERQEGGQQKQLCRFRCQERYKKERGQHNYKREDDEDEDEDEAEEEDENPYVFEDEDFTTKVKTEQGKVVLLPKFTQKSKLLHALEKYRLAVLVANPQAFVVPSHMDADSIFFVSWGRGTITKILENKRESINVRQGDIVSISSGTPFYIANNDENEKLYLVQFLRPVNLPGHFEVFHGPGGENPESFYRAFSWEILEAALKTSKDTLEKLFEKQDQGTIMKASKEQIRAMSRRGEGPKIWPFTEESTGSFKLFKKDPSQSNKYGQLFEAERIDYPPLEKLDMVVSYANITKGGMSVPFYNSRATKIAIVVSGEGCVEIACPHLSSSKSSHPSYKKLRARIRKDTVFIVPAGHPFATVASGNENLEIVCFEVNAEGNIRYTLAGKKNIIKVMEKEAKELAFKMEGEEVDKVFGKQDEEFFFQGPEWRKEKEGRADE
UniProt: Q8L5L5 IUIS: Ana o 1Explore peptide targets for mass spectrometry by adjusting the selection criteria below. Results from empirical and computational prediction tools have been aggregated for convenience.
1 | Peptide | 2 | Exp.3 | ESP4 | CONSeQ5 |
---|---|---|---|---|---|
K | FSFSLFLVSVLVLCLGFALAK | I | 0 | 0.14 | 0.1077 |
R | QYDEQQK | E | 0 | 0.234 | 0.12748 |
R | EHEEEEEEWGTGGVDEPSTHEPAEK | H | 0 | 0.495 | 0.35078 |
K | HLSQCMR | Q | 0 | 0.205 | 0.10588 |
R | QEGGQQK | Q | 0 | 0.21 | 0.0707 |
R | EDDEDEDEDEAEEEDENPYVFEDEDFTTK | V | 0 | 0.375 | 0.29778 |
K | LLHALEK | Y | 0 | 0.266 | 0.26478 |
R | LAVLVANPQAFVVPSHMDADSIFFVSWGR | G | 0 | 0.258 | 0.03106 |
R | QGDIVSISSGTPFYIANNDENEK | L | 0 | 0.599 | 0.30376 |
R | AFSWEILEAALK | T | 0 | 0.472 | 0.34216 |
K | QDQGTIMK | A | 0 | 0.232 | 0.27884 |
K | IWPFTEESTGSFK | L | 0 | 0.643 | 0.5408 |
K | DPSQSNK | Y | 0 | 0.173 | 0.04056 |
K | YGQLFEAER | I | 0 | 0.476 | 0.50222 |
R | IDYPPLEK | L | 0 | 0.286 | 0.53146 |
K | LDMVVSYANITK | G | 0 | 0.539 | 0.38068 |
K | GGMSVPFYNSR | A | 0 | 0.567 | 0.54376 |
K | IAIVVSGEGCVEIACPHLSSSK | S | 0 | 0.598 | 0.22574 |
K | SSHPSYK | K | 0 | 0.227 | 0.06872 |
K | MEGEEVDK | V | 0 | 0.236 | 0.27004 |
K | QDEEFFFQGPEWR | K | 0 | 0.685 | 0.33812 |
1 Previous amino acid (^ = Start of protein)
2 Next amino acid ($ = End of protein)
3 Exp. = Number of publications in which this peptide has been reported experimentally
4 ESP = ESP Predictor. Fusaro VA, et al. Nat Botechnol 2009; 27(2): 190-198. doi
5 CONSeQ = CONSeQuence. Eyers CE, et al. Mol Cell Proteomics 2011; 10(11). doi
Underline: Peptide occurs within the first 20 amino acids from the start of the protein. Use caution as the protein may contain a cleaved signaling sequence.
Strike-through: Peptide is present in a protein from another allergen species and is thus nonspecific.