Croote, D., Quake, S.R. Food allergen detection by mass spectrometry: the role of systems biology. npj Syst Biol Appl. 2016 Sep 29; 2:16022.
This rose plot enables visualization of proteotypic peptides. Each colored rose petal corresponds to a peptide and is bounded by thin gray petals, which represent tryptic cut sites. The radial magnitude of each peptide corresponds to the number of publications which report it.
Hover over a rose petal with your mouse to see the peptide. Click on a rose petal to see the species specificity of that peptide and add it to your cart.
LSVCFLILFHGCLASRQEWQQQDECQIDRLDALEPDNRVEYEAGTVEAWDPNHEQFRCAGVALVRHTIQPNGLLLPQYSNAPQLIYVVQGEGMTGISYPGCPETYQAPQQGRQQGQSGRFQDRHQKIRRFRRGDIIAIPAGVAHWCYNEGNSPVVTVTLLDVSNSQNQLDRTPRKFHLAGNPKDVFQQQQQHQSRGRNLFSGFDTELLAEAFQVDERLIKQLKSEDNRGGIVKVKDDELRVIRPSRSQSERGSESEEESEDEKRRWGQRDNGIEETICTMRLKENINDPARADIYTPEVGRLTTLNSLNLPILKWLQLSVEKGVLYKNALVLPHWNLNSHSIIYGCKGKGQVQVVDNFGNRVFDGEVREGQMLVVPQNFAVVKRAREERFEWISFKTNDRAMTSPLAGRTSVLGGMPEEVLANAFQISREDARKIKFNNQQTTLTSGESSHHMRDDA
UniProt: Q8GZP6 IUIS: Ana o 2Explore peptide targets for mass spectrometry by adjusting the selection criteria below. Results from empirical and computational prediction tools have been aggregated for convenience.
| 1 | Peptide | 2 | Exp.3 | ESP4 | CONSeQ5 |
|---|---|---|---|---|---|
| ^ | LSVCFLILFHGCLASR | Q | 0 | 0.337 | 0.12944 |
| R | QEWQQQDECQIDR | L | 0 | 0.418 | 0.34252 |
| R | LDALEPDNR | V | 1 | 0.415 | 0.48412 |
| R | VEYEAGTVEAWDPNHEQFR | C | 0 | 0.583 | 0.25348 |
| R | CAGVALVR | H | 2 | 0.303 | 0.47706 |
| R | QQGQSGR | F | 0 | 0.236 | 0.0793 |
| K | FHLAGNPK | D | 0 | 0.312 | 0.40838 |
| K | DVFQQQQQHQSR | G | 0 | 0.409 | 0.28934 |
| R | NLFSGFDTELLAEAFQVDER | L | 0 | 0.612 | 0.03988 |
| R | GSESEEESEDEK | R | 0 | 0.291 | 0.14792 |
| R | DNGIEETICTMR | L | 0 | 0.44 | 0.32418 |
| K | ENINDPAR | A | 0 | 0.22 | 0.23034 |
| R | ADIYTPEVGR | L | 4 | 0.534 | 0.91794 |
| R | LTTLNSLNLPILK | W | 0 | 0.649 | 0.41616 |
| K | WLQLSVEK | G | 0 | 0.286 | 0.34184 |
| K | NALVLPHWNLNSHSIIYGCK | G | 0 | 0.426 | 0.09132 |
| K | GQVQVVDNFGNR | V | 0 | 0.647 | 0.63354 |
| R | VFDGEVR | E | 1 | 0.264 | 0.52744 |
| R | EGQMLVVPQNFAVVK | R | 0 | 0.618 | 0.5592 |
| R | FEWISFK | T | 0 | 0.226 | 0.18112 |
| R | AMTSPLAGR | T | 4 | 0.346 | 0.82298 |
| R | TSVLGGMPEEVLANAFQISR | E | 0 | 0.724 | 0.02774 |
| K | FNNQQTTLTSGESSHHMR | D | 0 | 0.482 | 0.21916 |
1 Previous amino acid (^ = Start of protein)
2 Next amino acid ($ = End of protein)
3 Exp. = Number of publications in which this peptide has been reported experimentally
4 ESP = ESP Predictor. Fusaro VA, et al. Nat Botechnol 2009; 27(2): 190-198. doi
5 CONSeQ = CONSeQuence. Eyers CE, et al. Mol Cell Proteomics 2011; 10(11). doi
Underline: Peptide occurs within the first 20 amino acids from the start of the protein. Use caution as the protein may contain a cleaved signaling sequence.
Strike-through: Peptide is present in a protein from another allergen species and is thus nonspecific.