Croote, D., Quake, S.R. Food allergen detection by mass spectrometry: the role of systems biology. npj Syst Biol Appl. 2016 Sep 29; 2:16022.
This rose plot enables visualization of proteotypic peptides. Each colored rose petal corresponds to a peptide and is bounded by thin gray petals, which represent tryptic cut sites. The radial magnitude of each peptide corresponds to the number of publications which report it.
Hover over a rose petal with your mouse to see the peptide. Click on a rose petal to see the species specificity of that peptide and add it to your cart.
MGSIGAASMEFCFDVFKELKVHHANENIFYCPIAIMSALAMVYLGAKDSTRTQINKVVRFDKLPGFGDSIEAQCGTSVNVHSSLRDILNQITKPNDVYSFSLASRLYAEERYPILPEYLQCVKELYRGGLEPINFQTAADQARELINSWVESQTNGIIRNVLQPSSVDSQTAMVLVNAIVFKGLWEKAFKDEDTQAMPFRVTEQESKPVQMMYQIGLFRVASMASEKMKILELPFASGTMSMLVLLPDEVSGLEQLESIINFEKLTEWTSSNVMEERKIKVYLPRMKMEEKYNLTSVLMAMGITDVFSSSANLSGISSAESLKISQAVHAAHAEINEAGREVVGSAEAGVDAASVSEEFRADHPFLFCIKHIATNAVLFFGRCVSP
UniProt: P01012 IUIS: Gal d 2Explore peptide targets for mass spectrometry by adjusting the selection criteria below. Results from empirical and computational prediction tools have been aggregated for convenience.
1 | Peptide | 2 | Exp.3 | ESP4 | CONSeQ5 |
---|---|---|---|---|---|
^ | MGSIGAASMEFCFDVFK | E | 0 | 0.466 | 0.08274 |
K | VHHANENIFYCPIAIMSALAMVYLGAK | D | 0 | 0.318 | 0.0454 |
K | LPGFGDSIEAQCGTSVNVHSSLR | D | 0 | 0.708 | 0.20718 |
R | DILNQITKPNDVYSFSLASR | L | 3 | 0.457 | 0.11224 |
R | YPILPEYLQCVK | E | 6 | 0.578 | 0.45594 |
R | GGLEPINFQTAADQAR | E | 14 | 0.832 | 0.8953 |
R | ELINSWVESQTNGIIR | N | 6 | 0.512 | 0.29752 |
R | NVLQPSSVDSQTAMVLVNAIVFK | G | 4 | 0.532 | 0.05742 |
K | DEDTQAMPFR | V | 0 | 0.392 | 0.52476 |
R | VTEQESKPVQMMYQIGLFR | V | 3 | 0.254 | 0.139 |
R | VASMASEK | M | 2 | 0.208 | 0.37748 |
K | LTEWTSSNVMEER | K | 11 | 0.522 | 0.49116 |
K | ISQAVHAAHAEINEAGR | E | 6 | 0.537 | 0.40748 |
R | EVVGSAEAGVDAASVSEEFR | A | 3 | 0.493 | 0.44008 |
R | ADHPFLFCIK | H | 1 | 0.476 | 0.14986 |
K | HIATNAVLFFGR | C | 6 | 0.606 | 0.22878 |
1 Previous amino acid (^ = Start of protein)
2 Next amino acid ($ = End of protein)
3 Exp. = Number of publications in which this peptide has been reported experimentally
4 ESP = ESP Predictor. Fusaro VA, et al. Nat Botechnol 2009; 27(2): 190-198. doi
5 CONSeQ = CONSeQuence. Eyers CE, et al. Mol Cell Proteomics 2011; 10(11). doi
Underline: Peptide occurs within the first 20 amino acids from the start of the protein. Use caution as the protein may contain a cleaved signaling sequence.
Strike-through: Peptide is present in a protein from another allergen species and is thus nonspecific.