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Croote, D., Quake, S.R. Food allergen detection by mass spectrometry: the role of systems biology. npj Syst Biol Appl. 2016 Sep 29; 2:16022.

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Egg Protein: Gal d 6 | Ygp42

Empirical Proteotypic Peptide Explorer:

This rose plot enables visualization of proteotypic peptides. Each colored rose petal corresponds to a peptide and is bounded by thin gray petals, which represent tryptic cut sites. The radial magnitude of each peptide corresponds to the number of publications which report it.

Hover over a rose petal with your mouse to see the peptide. Click on a rose petal to see the species specificity of that peptide and add it to your cart.


Sequence - 1912 amino acids

MRGLISALVLTLVGSQHLNYQPDFGENKVYTYNYESILFSGIPEKGLARTGIRIRSEVEISGIGPKLCLIRIHSIEAAEYNGIWPTSSFSRSLKLTQALTGQLSIPIKFEYSNGHVGNLMAPDSVSDDGLNIYRGILNILELSLKKMQHSYSIQEAGIGGICNTTYAIQENKKANLVDVTKSKDLNSCEEKVQVVTGSAYTQPCQTCQQRNKNSRATATYNYKIKYTHNEAVITQAEVEEVHQFTPFHEITGGNAIVEARQKLALIEVQKQVAEVPPKEFQKRGSLQYQFGSELLQLPVHLFKIKDVERQIEERLQDLVETTYEQLPSDAPAKALKLMHLLRAANEENYESVWKQFSSRPAYRRYLLDLLPAAASHRSLRFLRHKMERQELTNWEIAQTVLVALHSSSPTQEVMEEATLIVKKHCPRSSSVLRKVCLLSYASLCHKRCSSPYSCSECLQVFHVFAGEALGKSNIEEVLLALKALGNVGHPASIKHIKKFLPGYAAGASELPLKVHETAVMALKSIGMRDPQMVQAITLEIFLNHKIHPRIRMLAAVVLLETKPGLPILMILVDAVLKEPSMQVASFIYSHLRALGRSTAPDLQMMASACRMAVRALSPKFDRSGYQFSKVFRFSMFKEFLMSGLAAKYFVLNNAGSLIPTMAVSQLRTHFLGRVADPIEVGIAAEGLQEMFVRGYSPDKDWETNYDFREILKKLSDWKALPRDKPFASGYLKMFGQELLFGRLDKDTLQNVLQVWYGPDEKIPSIRRLISSLQTGIGRQWTKALLLSEIRCIVPTCVGFPMETSFYYSSVTKVAGNVQAQITPSPRSDFRLTELLNSNVRLRSKMSLSMAKHMTFVIGINTNMIQAGLEAHTKVNAHVPVNVVATIQMKEKSIKAEIPPCKEETNLIIVSSKTFAVTRNIEDLAASKMTPVLLPEAVPDIMKMSFDSDSASGETDNIRDRQSVEDVSSGNSFSFGHPSSGKEPFIQSMCSNASTFGVQVCIEKKSVHAAFIRNVPLYNAIGEHALRMSFKPVYSDVPIEKIQVTIQAGDQAPTKMVRLVTFEDPERQESSRKEVMKRVKKILDDTDNQATRNSRSSSSSASSISESSESTTSTPSSSDSDNRASQGDPQINLKSRQSKANEKKFYPFGDSSSSGSSSSSSSSSSSSSDSSSSSRSSSSSDSSSSSSSSSSSSSSKSKSSSRSSKSNRSSSSSNSKDSSSSSSKSNSKGSSSSSSKASGTRQKAKKQSKTTSFPHASAAEGERSVHEQKQETQSSSSSSSRASSNSRSTSSSTSSSSESSGVSHRQWKQDREAETKRVKSQFNSHSSYDIPNEWETYLPKVYRLRFRSAHTHWHSGHRTSSSSSSSSSESGSSHSNSSSSDSSSRRSHMSDSSSSSSSHRHGEKAAHSSRRSPTSRAASAHHRPGSSLTRERNFLGDVIPPGITIVAQAVRSDNRNQGYQATAYVRSDAAKVDVQLVVVQLAETNWKACADAVILPLKAQARMRWGKECRDYRIAALATTGQMARKLAVQLKVQWGIIPSWIKKTSTALMRYVPGVALVLGFSEAHQRNPSRELIVRAVATSPRSIDTVIKVPGVTLYYQGLRVPFTLALGASSSSYETRDITAWNFLPEIASQIAQEDQSTCEVSKGDFKTFDRMSFTCSFNKSCNVVVAQDCTEHPKFIITTRKVDHQSLSREVHINTSSANITICPAADSSLLVTCNKESVLSDSGVSEYEKDNIKIYKNGKTVIVEAPIHGLKNVNFDGEILKVTVASWMRGKTCGVCGNNDREKHNELLMPNHKLAHSCSAFVHSWVLLEETCSGGCKLQRRYVKLNRNPTIDGEESTCYSVDPVLKCMKDCTPIEKTSVKVGFHCFPKATAVSLLEWQRSSDKKSASEDVVESVDADIDCTCTGDCS

UniProt: P87498   IUIS: Gal d 6

Peptide Selector Tool

Explore peptide targets for mass spectrometry by adjusting the selection criteria below. Results from empirical and computational prediction tools have been aggregated for convenience.

Exclude:
Peptide Characteristics:

Minimum length:

Maximum length:

1Peptide2Exp.3ESP4CONSeQ5
R GLISALVLTLVGSQHLNYQPDFGENK V 0 0.608 0.02742
K VYTYNYESILFSGIPEK G 0 0.603 0.1071
R SEVEISGIGPK L 0 0.461 0.85666
R IHSIEAAEYNGIWPTSSFSR S 0 0.579 0.09812
K LTQALTGQLSIPIK F 0 0.709 0.74722
K FEYSNGHVGNLMAPDSVSDDGLNIYR G 0 0.501 0.0933
R GILNILELSLK K 0 0.54 0.2882
K MQHSYSIQEAGIGGICNTTYAIQENK K 0 0.372 0.14668
K ANLVDVTK S 0 0.339 0.6666
K DLNSCEEK V 0 0.273 0.17108
K VQVVTGSAYTQPCQTCQQR N 0 0.565 0.2918
R ATATYNYK I 0 0.243 0.31368
K LALIEVQK Q 0 0.282 0.39942
K QVAEVPPK E 0 0.3 0.51178
R GSLQYQFGSELLQLPVHLFK I 0 0.471 0.05084
R LQDLVETTYEQLPSDAPAK A 0 0.898 0.3189
R AANEENYESVWK Q 0 0.476 0.434
K QFSSRPAYR R 0 0.225 0.2819
R YLLDLLPAAASHR S 3 0.613 0.44098
K VCLLSYASLCHK R 0 0.404 0.21322
R CSSPYSCSECLQVFHVFAGEALGK S 0 0.48 0.1035
K SNIEEVLLALK A 0 0.627 0.53216
K ALGNVGHPASIK H 0 0.701 0.7638
K FLPGYAAGASELPLK V 0 0.78 0.593
K VHETAVMALK S 0 0.387 0.33694
R DPQMVQAITLEIFLNHK I 0 0.669 0.08954
R MLAAVVLLETKPGLPILMILVDAVLK E 0 0.255 0.1512
K EPSMQVASFIYSHLR A 0 0.579 0.22232
R STAPDLQMMASACR M 0 0.471 0.64472
R SGYQFSK V 0 0.255 0.09542
K EFLMSGLAAK Y 0 0.361 0.54982
K YFVLNNAGSLIPTMAVSQLR T 0 0.512 0.02202
R VADPIEVGIAAEGLQEMFVR G 0 0.609 0.0674
K DWETNYDFR E 0 0.472 0.1785
R DKPFASGYLK M 0 0.253 0.58996
K MFGQELLFGR L 0 0.447 0.2447
K DTLQNVLQVWYGPDEK I 0 0.712 0.31382
R LISSLQTGIGR Q 0 0.553 0.78958
K ALLLSEIR C 0 0.313 0.40064
R CIVPTCVGFPMETSFYYSSVTK V 0 0.46 0.16816
K VAGNVQAQITPSPR S 1 0.821 0.89278
R LTELLNSNVR L 0 0.68 0.65566
K MSLSMAK H 0 0.211 0.22664
K HMTFVIGINTNMIQAGLEAHTK V 0 0.445 0.0812
K VNAHVPVNVVATIQMK E 0 0.558 0.45858
K AEIPPCK E 0 0.217 0.24598
K EETNLIIVSSK T 0 0.542 0.67168
R NIEDLAASK M 0 0.354 0.71116
K MTPVLLPEAVPDIMK M 0 0.588 0.51466
K MSFDSDSASGETDNIR D 0 0.538 0.52928
R QSVEDVSSGNSFSFGHPSSGK E 0 0.601 0.4746
K EPFIQSMCSNASTFGVQVCIEK K 0 0.396 0.06716
K SVHAAFIR N 0 0.431 0.37462
R NVPLYNAIGEHALR M 0 0.757 0.6841
R MSFKPVYSDVPIEK I 0 0.368 0.6395
K IQVTIQAGDQAPTK M 0 0.692 0.90964
R LVTFEDPER Q 0 0.517 0.78462
K ILDDTDNQATR N 0 0.602 0.57982
R SSSSSASSISESSESTTSTPSSSDSDNR A 0 0.401 0.35654
R ASQGDPQINLK S 0 0.437 0.76168
R SSSSSDSSSSSSSSSSSSSSK S 0 0.426 0.32536
R SSSSSNSK D 0 0.162 0.1034
K DSSSSSSK S 0 0.175 0.08628
K GSSSSSSK A 0 0.175 0.11276
K TTSFPHASAAEGER S 0 0.67 0.5301
K QETQSSSSSSSR A 0 0.299 0.17948
R STSSSTSSSSESSGVSHR Q 0 0.472 0.25636
K SQFNSHSSYDIPNEWETYLPK V 0 0.566 0.26434
R SAHTHWHSGHR T 0 0.375 0.14058
R TSSSSSSSSSESGSSHSNSSSSDSSSR R 0 0.241 0.3135
R SHMSDSSSSSSSHR H 0 0.369 0.18782
R AASAHHRPGSSLTR E 0 0.21 0.17896
R NFLGDVIPPGITIVAQAVR S 0 0.769 0.16534
R NQGYQATAYVR S 0 0.47 0.50212
K VDVQLVVVQLAETNWK A 0 0.507 0.22586
K ACADAVILPLK A 0 0.561 0.5682
R IAALATTGQMAR K 0 0.466 0.83558
K VQWGIIPSWIK K 0 0.409 0.36078
K TSTALMR Y 0 0.246 0.21194
R YVPGVALVLGFSEAHQR N 0 0.695 0.23404
R AVATSPR S 0 0.223 0.09352
R SIDTVIK V 0 0.262 0.32626
K VPGVTLYYQGLR V 0 0.604 0.48822
R VPFTLALGASSSSYETR D 0 0.692 0.50018
R DITAWNFLPEIASQIAQEDQSTCEVSK G 0 0.418 0.05934
R MSFTCSFNK S 0 0.313 0.21946
K SCNVVVAQDCTEHPK F 0 0.657 0.32258
K VDHQSLSR E 0 0.311 0.2097
R EVHINTSSANITICPAADSSLLVTCNK E 0 0.562 0.16026
K ESVLSDSGVSEYEK D 0 0.551 0.63544
K TVIVEAPIHGLK N 1 0.727 0.66656
K NVNFDGEILK V 1 0.517 0.66768
K VTVASWMR G 0 0.257 0.38518
K TCGVCGNNDR E 0 0.438 0.23746
K HNELLMPNHK L 0 0.337 0.30326
K LAHSCSAFVHSWVLLEETCSGGCK L 0 0.436 0.09768
R NPTIDGEESTCYSVDPVLK C 0 0.765 0.3396
K DCTPIEK T 0 0.244 0.12878
K VGFHCFPK A 0 0.298 0.25564
K ATAVSLLEWQR S 1 0.521 0.544
K SASEDVVESVDADIDCTCTGDCS $ 0 0.358 0.39632

1 Previous amino acid (^ = Start of protein)

2 Next amino acid ($ = End of protein)

3 Exp. = Number of publications in which this peptide has been reported experimentally

4 ESP = ESP Predictor. Fusaro VA, et al. Nat Botechnol 2009; 27(2): 190-198. doi

5 CONSeQ = CONSeQuence. Eyers CE, et al. Mol Cell Proteomics 2011; 10(11). doi

Underline: Peptide occurs within the first 20 amino acids from the start of the protein. Use caution as the protein may contain a cleaved signaling sequence.

Strike-through: Peptide is present in a protein from another allergen species and is thus nonspecific.

 

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