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Croote, D., Quake, S.R. Food allergen detection by mass spectrometry: the role of systems biology. npj Syst Biol Appl. 2016 Sep 29; 2:16022.

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Hazelnut Protein: Cor a 11 | 7S Seed Storage Globulin (Vicilin-Like)

Empirical Proteotypic Peptide Explorer:

This rose plot enables visualization of proteotypic peptides. Each colored rose petal corresponds to a peptide and is bounded by thin gray petals, which represent tryptic cut sites. The radial magnitude of each peptide corresponds to the number of publications which report it.

Hover over a rose petal with your mouse to see the peptide. Click on a rose petal to see the species specificity of that peptide and add it to your cart.


Sequence - 448 amino acids

MLPKEDPELKKCKHKCRDERQFDEQQRRDGKQICEEKARERQQEEGNSSEESYGKEQEENPYVFQDEHFESRVKTEEGRVQVLENFTKRSRLLSGIENFRLAILEANPHTFISPAHFDAELVLFVAKGRATITMVREEKRESFNVEHGDIIRIPAGTPVYMINRDENEKLFIVKILQPVSAPGHFEAFYGAGGEDPESFYRAFSWEVLEAALKVRREQLEKVFGEQSKGSIVKASREKIRALSQHEEGPPRIWPFGGESSGPINLLHKHPSQSNQFGRLYEAHPDDHKQLQDLDLMVSFANITKGSMAGPYYNSRATKISVVVEGEGFFEMACPHLSSSSGSYQKISARLRRGVVFVAPAGHPVAVIASQNNNLQVLCFEVNAHGNSRFPLAGKGNIVNEFERDAKELAFNLPSREVERIFKNQDQAFFFPGPNKQQEEGGRGGRAFE

UniProt: Q8S4P9   IUIS: Cor a 11

Peptide Selector Tool

Explore peptide targets for mass spectrometry by adjusting the selection criteria below. Results from empirical and computational prediction tools have been aggregated for convenience.

Exclude:
Peptide Characteristics:

Minimum length:

Maximum length:

1Peptide2Exp.3ESP4CONSeQ5
R QFDEQQR R 0 0.233 0.18486
R QQEEGNSSEESYGK E 0 0.444 0.15866
K EQEENPYVFQDEHFESR V 0 0.556 0.3523
R VQVLENFTK R 0 0.373 0.4973
R LLSGIENFR L 2 0.575 0.40548
R LAILEANPHTFISPAHFDAELVLFVAK G 0 0.433 0.04676
R ATITMVR E 0 0.214 0.3594
R ESFNVEHGDIIR I 0 0.692 0.48896
R IPAGTPVYMINR D 0 0.683 0.66222
K ILQPVSAPGHFEAFYGAGGEDPESFYR A 0 0.68 0.1441
R AFSWEVLEAALK V 2 0.497 0.39244
K VFGEQSK G 0 0.216 0.08504
R ALSQHEEGPPR I 0 0.487 0.38126
R IWPFGGESSGPINLLHK H 0 0.785 0.31768
K HPSQSNQFGR L 0 0.405 0.18242
R LYEAHPDDHK Q 0 0.449 0.22676
K QLQDLDLMVSFANITK G 0 0.65 0.184
K GSMAGPYYNSR A 0 0.441 0.3709
K ISVVVEGEGFFEMACPHLSSSSGSYQK I 0 0.431 0.07716
K GNIVNEFER D 0 0.457 0.58736
K ELAFNLPSR E 2 0.553 0.7591
K NQDQAFFFPGPNK Q 0 0.728 0.58752
K QQEEGGR G 0 0.225 0.06086

1 Previous amino acid (^ = Start of protein)

2 Next amino acid ($ = End of protein)

3 Exp. = Number of publications in which this peptide has been reported experimentally

4 ESP = ESP Predictor. Fusaro VA, et al. Nat Botechnol 2009; 27(2): 190-198. doi

5 CONSeQ = CONSeQuence. Eyers CE, et al. Mol Cell Proteomics 2011; 10(11). doi

Underline: Peptide occurs within the first 20 amino acids from the start of the protein. Use caution as the protein may contain a cleaved signaling sequence.

Strike-through: Peptide is present in a protein from another allergen species and is thus nonspecific.

 

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