Croote, D., Quake, S.R. Food allergen detection by mass spectrometry: the role of systems biology. npj Syst Biol Appl. 2016 Sep 29; 2:16022.
This rose plot enables visualization of proteotypic peptides. Each colored rose petal corresponds to a peptide and is bounded by thin gray petals, which represent tryptic cut sites. The radial magnitude of each peptide corresponds to the number of publications which report it.
Hover over a rose petal with your mouse to see the peptide. Click on a rose petal to see the species specificity of that peptide and add it to your cart.
MAKLILVSFSLCLLVLFNGCLGINVGLRRQQQRYFGECNLDRLNALEPTNRIEAEACQIESWDHNDQQFQCAGVAVIRRTIEPNGLLLPQYSNAPELIYIERGRGITGVLFPGCPETFEDPQQQSQQGQRQGQGQSQRSEQDRHQKIRHFREGDIIALPAGVAHWCYNDGDSPVVTVSLLHTNNYANQLDENPRHFYLAGNPDDEHQRQGQQQFGQRRRQQQHSHGEQGEQEQQGEGNNVFSGFDAEFLADAFNVDVDTARRLQSNQDKRRNIVKVEGRLQVVRPERSRQEWERQERQERESEQERERQRRQGGRGRDVNGFEETICSLRLRENICTRSRADIYTEQVGRINTVNSNTLPVLRWLQLSAERGDLQREGLYVPHWNLNAHSVVYAIRGRARVQVVDDNGNTVFDDELRQGQVLTIPQNFAVAKRAESEGFEWVAFKTNDNAQISPLAGRTSAIRALPDDVLANAFQISREEARRLKYNRQETTLVRSSRSSSERKRRSESEGRAEA
UniProt: Q8W1C2 IUIS: Cor a 9Explore peptide targets for mass spectrometry by adjusting the selection criteria below. Results from empirical and computational prediction tools have been aggregated for convenience.
| 1 | Peptide | 2 | Exp.3 | ESP4 | CONSeQ5 |
|---|---|---|---|---|---|
| K | LILVSFSLCLLVLFNGCLGINVGLR | R | 0 | 0.226 | 0.10194 |
| R | YFGECNLDR | L | 0 | 0.501 | 0.26514 |
| R | LNALEPTNR | I | 2 | 0.465 | 0.83564 |
| R | IEAEACQIESWDHNDQQFQCAGVAVIR | R | 0 | 0.341 | 0.1196 |
| R | TIEPNGLLLPQYSNAPELIYIER | G | 0 | 0.775 | 0.06532 |
| R | GITGVLFPGCPETFEDPQQQSQQGQR | Q | 0 | 0.712 | 0.4115 |
| R | QGQGQSQR | S | 0 | 0.258 | 0.18488 |
| R | HFYLAGNPDDEHQR | Q | 0 | 0.642 | 0.2427 |
| R | QGQQQFGQR | R | 0 | 0.323 | 0.3442 |
| R | LQSNQDK | R | 0 | 0.222 | 0.07686 |
| R | LQVVRPER | S | 0 | 0.255 | 0.48656 |
| R | DVNGFEETICSLR | L | 0 | 0.642 | 0.56506 |
| R | ADIYTEQVGR | I | 8 | 0.479 | 0.80932 |
| R | INTVNSNTLPVLR | W | 5 | 0.76 | 0.82334 |
| R | WLQLSAER | G | 3 | 0.304 | 0.40794 |
| R | EGLYVPHWNLNAHSVVYAIR | G | 0 | 0.456 | 0.07602 |
| R | VQVVDDNGNTVFDDELR | Q | 0 | 0.716 | 0.29502 |
| R | QGQVLTIPQNFAVAK | R | 6 | 0.765 | 0.8215 |
| R | AESEGFEWVAFK | T | 0 | 0.505 | 0.42388 |
| K | TNDNAQISPLAGR | T | 2 | 0.725 | 0.92298 |
| R | ALPDDVLANAFQISR | E | 7 | 0.879 | 0.79128 |
| R | QETTLVR | S | 0 | 0.265 | 0.31886 |
1 Previous amino acid (^ = Start of protein)
2 Next amino acid ($ = End of protein)
3 Exp. = Number of publications in which this peptide has been reported experimentally
4 ESP = ESP Predictor. Fusaro VA, et al. Nat Botechnol 2009; 27(2): 190-198. doi
5 CONSeQ = CONSeQuence. Eyers CE, et al. Mol Cell Proteomics 2011; 10(11). doi
Underline: Peptide occurs within the first 20 amino acids from the start of the protein. Use caution as the protein may contain a cleaved signaling sequence.
Strike-through: Peptide is present in a protein from another allergen species and is thus nonspecific.