Croote, D., Quake, S.R. Food allergen detection by mass spectrometry: the role of systems biology. npj Syst Biol Appl. 2016 Sep 29; 2:16022.
This rose plot enables visualization of proteotypic peptides. Each colored rose petal corresponds to a peptide and is bounded by thin gray petals, which represent tryptic cut sites. The radial magnitude of each peptide corresponds to the number of publications which report it.
Hover over a rose petal with your mouse to see the peptide. Click on a rose petal to see the species specificity of that peptide and add it to your cart.
MVKLAHLLVATVGVLLVLNGCLARQSLGVPPQVKDACNLDNLDVLQPTEVIKSEAGQVEYWDHNHPQIRCAGVSIARLVIQKGGLYLPTFFSSPFISYVVQGMGISGRVIPGCAETFMDSQPMQGQQGQQQGQQGQQGQQGQQGQQGQQGQQGQQGQQGQQGQQGQQGQQGQGFRDMHQKVEHVRHGDAIAMTPGSAQWIYNTGDQPLIIVSLIDIANYQNQLDRNPRTFRLAGNNQQGSSQQQQQQQQNILSGFDPQVLAQALKIDVRLAQELQNQQDKRGNIVRVKGPFQVVRPPLRQAYESEQWRHPRGPPQSPQDNGLEETICSMRTHENIDDPARADIYKPNLGRVTSVNSYTLPILQYIRLSATRGILQGSAMVLPKYNMNANEILYCTQGQARIQVVNDNGQNVLDQQVQKGQLVVIPQGFAYVVQSQNNFEWISFKTNANAMISTLAGRTSALRALPLEVITNAYQISLEEARKIKFNTLETTLTRARGGQQPQLIEEIVEV
UniProt: Q2TLW0 IUIS: Sin a 2Explore peptide targets for mass spectrometry by adjusting the selection criteria below. Results from empirical and computational prediction tools have been aggregated for convenience.
| 1 | Peptide | 2 | Exp.3 | ESP4 | CONSeQ5 |
|---|---|---|---|---|---|
| K | LAHLLVATVGVLLVLNGCLAR | Q | 0 | 0.445 | 0.15558 |
| R | QSLGVPPQVK | D | 0 | 0.517 | 0.69604 |
| K | DACNLDNLDVLQPTEVIK | S | 0 | 0.77 | 0.18788 |
| K | SEAGQVEYWDHNHPQIR | C | 0 | 0.467 | 0.2239 |
| R | CAGVSIAR | L | 0 | 0.292 | 0.45224 |
| K | GGLYLPTFFSSPFISYVVQGMGISGR | V | 0 | 0.193 | 0.1059 |
| R | LAQELQNQQDK | R | 0 | 0.364 | 0.47388 |
| K | GPFQVVRPPLR | Q | 1 | 0.375 | 0.38516 |
| R | QAYESEQWR | H | 0 | 0.319 | 0.20598 |
| R | GPPQSPQDNGLEETICSMR | T | 0 | 0.731 | 0.52194 |
| R | THENIDDPAR | A | 0 | 0.412 | 0.1836 |
| R | ADIYKPNLGR | V | 0 | 0.241 | 0.6561 |
| R | VTSVNSYTLPILQYIR | L | 0 | 0.552 | 0.30316 |
| R | GILQGSAMVLPK | Y | 0 | 0.512 | 0.74282 |
| K | YNMNANEILYCTQGQAR | I | 0 | 0.527 | 0.12634 |
| R | IQVVNDNGQNVLDQQVQK | G | 0 | 0.656 | 0.4302 |
| K | GQLVVIPQGFAYVVQSQNNFEWISFK | T | 0 | 0.299 | 0.06018 |
| K | TNANAMISTLAGR | T | 0 | 0.498 | 0.88378 |
| R | ALPLEVITNAYQISLEEAR | K | 0 | 0.745 | 0.07226 |
| K | FNTLETTLTR | A | 0 | 0.527 | 0.5031 |
| R | GGQQPQLIEEIVEV | $ | 0 | 0.603 | 0.55586 |
1 Previous amino acid (^ = Start of protein)
2 Next amino acid ($ = End of protein)
3 Exp. = Number of publications in which this peptide has been reported experimentally
4 ESP = ESP Predictor. Fusaro VA, et al. Nat Botechnol 2009; 27(2): 190-198. doi
5 CONSeQ = CONSeQuence. Eyers CE, et al. Mol Cell Proteomics 2011; 10(11). doi
Underline: Peptide occurs within the first 20 amino acids from the start of the protein. Use caution as the protein may contain a cleaved signaling sequence.
Strike-through: Peptide is present in a protein from another allergen species and is thus nonspecific.