Croote, D., Quake, S.R. Food allergen detection by mass spectrometry: the role of systems biology. npj Syst Biol Appl. 2016 Sep 29; 2:16022.
This rose plot enables visualization of proteotypic peptides. Each colored rose petal corresponds to a peptide and is bounded by thin gray petals, which represent tryptic cut sites. The radial magnitude of each peptide corresponds to the number of publications which report it.
Hover over a rose petal with your mouse to see the peptide. Click on a rose petal to see the species specificity of that peptide and add it to your cart.
KTDPELKQCKHQCKVQRQYDEEQKEQCAKGCEKYYKEKKGREQEEEEEEEWGSGRGRGDEFSTHEPGEKRLSQCMKQCERQDGGQQKQLCRFRCQEKYKKERREHSYSRDEEEEEEGDEEQEEEDENPYVFEDEHFTTRVKTEQGKVVVLPKFTKRSKLLRGLEKYRLAFLVANPQAFVVPNHMDADSIFFVSWGRGTITKIRENKRESMNVKQGDIIRIRAGTPFYIVNTDENEKLYIVKLLQPVNLPGHYEVFHGPGGENPESFYRAFSREVLEAALKTPRDKLEKLFEKQDEGAIVKASKEQIRAMSRRGEGPSIWPFTGKSTGTFNLFKKDPSQSNNYGQLFESEFKDYPPLQELDIMVSYVNITKGGMSGPFYNSRATKIAIVVSGEGRLEIACPHLSSSKNSGQEKSGPSYKKLSSSIRTDSVFVVPAGHPFVTVASGNQNLEILCFEVNAEGNIRYTLAGKKNIIEVMEKEAKELAFKTKGEEVDKVFGKQDEEFFFQGPKWRQHQQGRADE
UniProt: B4X640 IUIS: Pis v 3Explore peptide targets for mass spectrometry by adjusting the selection criteria below. Results from empirical and computational prediction tools have been aggregated for convenience.
1 | Peptide | 2 | Exp.3 | ESP4 | CONSeQ5 |
---|---|---|---|---|---|
R | QYDEEQK | E | 0 | 0.229 | 0.09048 |
R | EQEEEEEEEWGSGR | G | 0 | 0.325 | 0.26662 |
R | GDEFSTHEPGEK | R | 0 | 0.498 | 0.16022 |
R | QDGGQQK | Q | 0 | 0.202 | 0.08164 |
R | DEEEEEEGDEEQEEEDENPYVFEDEHFTTR | V | 0 | 0.457 | 0.33464 |
R | LAFLVANPQAFVVPNHMDADSIFFVSWGR | G | 0 | 0.234 | 0.02188 |
R | AGTPFYIVNTDENEK | L | 0 | 0.728 | 0.81198 |
K | LLQPVNLPGHYEVFHGPGGENPESFYR | A | 0 | 0.689 | 0.16616 |
R | EVLEAALK | T | 0 | 0.264 | 0.52418 |
K | QDEGAIVK | A | 0 | 0.242 | 0.54598 |
R | GEGPSIWPFTGK | S | 0 | 0.57 | 0.53534 |
K | STGTFNLFK | K | 0 | 0.46 | 0.48454 |
K | DPSQSNNYGQLFESEFK | D | 0 | 0.727 | 0.47986 |
K | DYPPLQELDIMVSYVNITK | G | 0 | 0.745 | 0.1204 |
K | GGMSGPFYNSR | A | 0 | 0.508 | 0.38488 |
K | IAIVVSGEGR | L | 0 | 0.433 | 0.79146 |
R | LEIACPHLSSSK | N | 0 | 0.608 | 0.63818 |
K | NIIEVMEK | E | 0 | 0.237 | 0.4433 |
K | QDEEFFFQGPK | W | 0 | 0.564 | 0.56712 |
1 Previous amino acid (^ = Start of protein)
2 Next amino acid ($ = End of protein)
3 Exp. = Number of publications in which this peptide has been reported experimentally
4 ESP = ESP Predictor. Fusaro VA, et al. Nat Botechnol 2009; 27(2): 190-198. doi
5 CONSeQ = CONSeQuence. Eyers CE, et al. Mol Cell Proteomics 2011; 10(11). doi
Underline: Peptide occurs within the first 20 amino acids from the start of the protein. Use caution as the protein may contain a cleaved signaling sequence.
Strike-through: Peptide is present in a protein from another allergen species and is thus nonspecific.