Croote, D., Quake, S.R. Food allergen detection by mass spectrometry: the role of systems biology. npj Syst Biol Appl. 2016 Sep 29; 2:16022.
This rose plot enables visualization of proteotypic peptides. Each colored rose petal corresponds to a peptide and is bounded by thin gray petals, which represent tryptic cut sites. The radial magnitude of each peptide corresponds to the number of publications which report it.
Hover over a rose petal with your mouse to see the peptide. Click on a rose petal to see the species specificity of that peptide and add it to your cart.
MSCGGRLCLVLFALLLASAVVASESKDPELKQCKHQCKAQQQISKEQKEACIQACKEYIRQKHQGEHGRGGGDILEEEVWNRKSPIERLRECSRGCEQQHGEQREECLRRCQEEYQREKGRQDDDNPTDPEKQYQQCRLQCRRQGEGGGFSREHCERRREEKYREQQGREGGRGEMYEGREREEEQEEQGRGRIPYVFEDQHFITGFRTQHGRMRVLQKFTDRSELLRGIENYRVAILEAEPQTFIVPNHWDAESVVFVAKGRGTISLVRQDRRESLNIKQGDILKINAGTTAYLINRDNNERLVLAKLLQPVSTPGEFELFFGAGGENPESFFKSFSDEILEAAFNTRRDRLQRIFGQQRQGVIVKASEEQVRAMSRHEEGGIWPFGGESKGTINIYQQRPTHSNQYGQLHEVDASQYRQLRDLDLTVSLANITQGAMTAPHYNSKATKIALVVDGEGYFEMACPHMSRSRGSYQGETRGRPSYQRVASRLTRGTVVIIPAGHPFVAVASSNQNLQVLCFEVNANNNEKFPLAGRRNVMNQLEREAKELAFGMPAREVEEVSRSQQEEFFFKGPRQQQQGRADA
UniProt: Q9AUD0 IUIS: Ses i 3Explore peptide targets for mass spectrometry by adjusting the selection criteria below. Results from empirical and computational prediction tools have been aggregated for convenience.
1 | Peptide | 2 | Exp.3 | ESP4 | CONSeQ5 |
---|---|---|---|---|---|
R | LCLVLFALLLASAVVASESK | D | 0 | 0.351 | 0.14706 |
K | AQQQISK | E | 0 | 0.223 | 0.09108 |
K | EACIQACK | E | 0 | 0.271 | 0.32506 |
K | HQGEHGR | G | 0 | 0.18 | 0.0682 |
R | GGGDILEEEVWNR | K | 0 | 0.526 | 0.6129 |
R | GCEQQHGEQR | E | 0 | 0.268 | 0.18042 |
R | CQEEYQR | E | 0 | 0.239 | 0.12396 |
R | QDDDNPTDPEK | Q | 0 | 0.328 | 0.1528 |
R | QGEGGGFSR | E | 0 | 0.355 | 0.304 |
R | GEMYEGR | E | 0 | 0.253 | 0.14312 |
R | EEEQEEQGR | G | 0 | 0.22 | 0.21536 |
R | IPYVFEDQHFITGFR | T | 0 | 0.561 | 0.10622 |
R | VAILEAEPQTFIVPNHWDAESVVFVAK | G | 0 | 0.487 | 0.07048 |
R | GTISLVR | Q | 0 | 0.26 | 0.504 |
K | INAGTTAYLINR | D | 0 | 0.554 | 0.79502 |
K | LLQPVSTPGEFELFFGAGGENPESFFK | S | 0 | 0.611 | 0.09024 |
K | SFSDEILEAAFNTR | R | 0 | 0.727 | 0.71546 |
K | ASEEQVR | A | 0 | 0.206 | 0.09892 |
R | HEEGGIWPFGGESK | G | 0 | 0.64 | 0.43746 |
K | GTINIYQQRPTHSNQYGQLHEVDASQYR | Q | 0 | 0.223 | 0.24304 |
R | DLDLTVSLANITQGAMTAPHYNSK | A | 0 | 0.725 | 0.08584 |
K | IALVVDGEGYFEMACPHMSR | S | 0 | 0.524 | 0.03178 |
R | GSYQGETR | G | 0 | 0.28 | 0.21044 |
R | GRPSYQR | V | 0 | 0.231 | 0.12644 |
R | NVMNQLER | E | 0 | 0.251 | 0.46418 |
K | ELAFGMPAR | E | 0 | 0.377 | 0.64234 |
R | EVEEVSR | S | 0 | 0.183 | 0.24624 |
R | SQQEEFFFK | G | 0 | 0.435 | 0.30702 |
1 Previous amino acid (^ = Start of protein)
2 Next amino acid ($ = End of protein)
3 Exp. = Number of publications in which this peptide has been reported experimentally
4 ESP = ESP Predictor. Fusaro VA, et al. Nat Botechnol 2009; 27(2): 190-198. doi
5 CONSeQ = CONSeQuence. Eyers CE, et al. Mol Cell Proteomics 2011; 10(11). doi
Underline: Peptide occurs within the first 20 amino acids from the start of the protein. Use caution as the protein may contain a cleaved signaling sequence.
Strike-through: Peptide is present in a protein from another allergen species and is thus nonspecific.