Croote, D., Quake, S.R. Food allergen detection by mass spectrometry: the role of systems biology. npj Syst Biol Appl. 2016 Sep 29; 2:16022.
This rose plot enables visualization of proteotypic peptides. Each colored rose petal corresponds to a peptide and is bounded by thin gray petals, which represent tryptic cut sites. The radial magnitude of each peptide corresponds to the number of publications which report it.
Hover over a rose petal with your mouse to see the peptide. Click on a rose petal to see the species specificity of that peptide and add it to your cart.
MALTSLLSFFIVVTLLIRGLSAQLAGEQDFYWQDLQSQQQHKLQARTDCRVERLTAQEPTIRFESEAGLTEFWDRNNQQFECAGVAAVRNVIQPRGLLLPHYNNAPQLLYVVRGRGIQGTVIPGCAETFERDTQPRQDRRRRFMDRHQKVRQFRQGDILALPAGLTLWFYNNGGEPLITVALLDTGNAANQLDQTFRHFFLAGNPQGGRQSYFGRPQTEKQQGETKNIFNGFDDEILADAFGVDVQTARRLKGQDDLRGRIVRAERLDIVLPGEEEEERWERDPYSGANGLEETLCTAKLRENLDEPARADVYNPHGGRISSLNSLTLPVLSWLRLSAEKGVLYRNGLVAPHWNLNAHSIIYITRGSGRFQVVGHTGRSVFDGVVREGQLIIVPQNYVVAKRASQDEGLEWISFKTNDNAMTSQLAGRLSAIRAMPEEVVMTAYQVSRDEARRLKYNREESRVFSSTSRYSWPRSSRPMSYMPKPFEYVLDVIKSMM
UniProt: Q9AUD2 IUIS: Ses i 7Explore peptide targets for mass spectrometry by adjusting the selection criteria below. Results from empirical and computational prediction tools have been aggregated for convenience.
| 1 | Peptide | 2 | Exp.3 | ESP4 | CONSeQ5 |
|---|---|---|---|---|---|
| ^ | MALTSLLSFFIVVTLLIR | G | 0 | 0.166 | 0.1555 |
| R | GLSAQLAGEQDFYWQDLQSQQQHK | L | 0 | 0.474 | 0.29374 |
| R | LTAQEPTIR | F | 0 | 0.391 | 0.8503 |
| R | FESEAGLTEFWDR | N | 0 | 0.566 | 0.42034 |
| R | NNQQFECAGVAAVR | N | 0 | 0.599 | 0.67546 |
| R | GLLLPHYNNAPQLLYVVR | G | 0 | 0.672 | 0.10806 |
| R | GIQGTVIPGCAETFER | D | 0 | 0.757 | 0.72928 |
| R | HFFLAGNPQGGR | Q | 0 | 0.725 | 0.4257 |
| R | QSYFGRPQTEK | Q | 0 | 0.25 | 0.29294 |
| K | NIFNGFDDEILADAFGVDVQTAR | R | 0 | 0.523 | 0.0296 |
| R | LDIVLPGEEEEER | W | 0 | 0.665 | 0.6747 |
| R | DPYSGANGLEETLCTAK | L | 0 | 0.764 | 0.77016 |
| R | ENLDEPAR | A | 0 | 0.246 | 0.23206 |
| R | ADVYNPHGGR | I | 0 | 0.514 | 0.28226 |
| R | ISSLNSLTLPVLSWLR | L | 0 | 0.444 | 0.19076 |
| R | NGLVAPHWNLNAHSIIYITR | G | 0 | 0.472 | 0.09394 |
| R | FQVVGHTGR | S | 0 | 0.507 | 0.4516 |
| R | SVFDGVVR | E | 0 | 0.404 | 0.59792 |
| R | EGQLIIVPQNYVVAK | R | 0 | 0.672 | 0.6205 |
| R | ASQDEGLEWISFK | T | 0 | 0.602 | 0.5615 |
| K | TNDNAMTSQLAGR | L | 0 | 0.506 | 0.5546 |
| R | AMPEEVVMTAYQVSR | D | 0 | 0.58 | 0.5363 |
| R | VFSSTSR | Y | 0 | 0.253 | 0.17892 |
| R | SSRPMSYMPKPFEYVLDVIK | S | 0 | 0.257 | 0.22786 |
1 Previous amino acid (^ = Start of protein)
2 Next amino acid ($ = End of protein)
3 Exp. = Number of publications in which this peptide has been reported experimentally
4 ESP = ESP Predictor. Fusaro VA, et al. Nat Botechnol 2009; 27(2): 190-198. doi
5 CONSeQ = CONSeQuence. Eyers CE, et al. Mol Cell Proteomics 2011; 10(11). doi
Underline: Peptide occurs within the first 20 amino acids from the start of the protein. Use caution as the protein may contain a cleaved signaling sequence.
Strike-through: Peptide is present in a protein from another allergen species and is thus nonspecific.