Croote, D., Quake, S.R. Food allergen detection by mass spectrometry: the role of systems biology. npj Syst Biol Appl. 2016 Sep 29; 2:16022.
This rose plot enables visualization of proteotypic peptides. Each colored rose petal corresponds to a peptide and is bounded by thin gray petals, which represent tryptic cut sites. The radial magnitude of each peptide corresponds to the number of publications which report it.
Hover over a rose petal with your mouse to see the peptide. Click on a rose petal to see the species specificity of that peptide and add it to your cart.
MAKLVFSLCFLLFSGCCFAFSSREQPQQNECQIQKLNALKPDNRIESEGGLIETWNPNNKPFQCAGVALSRCTLNRNALRRPSYTNGPQEIYIQQGKGIFGMIYPGCPSTFEEPQQPQQRGQSSRPQDRHQKIYNFREGDLIAVPTGVAWWMYNNEDTPVVAVSIIDTNSLENQLDQMPRRFYLAGNQEQEFLKYQQEQGGHQSQKGKHQQEEENEGGSILSGFTLEFLEHAFSVDKQIAKNLQGENEGEDKGAIVTVKGGLSVIKPPTDEQQQRPQEEEEEEEDEKPQCKGKDKHCQRPRGSQSKSRRNGIDETICTMRLRHNIGQTSSPDIYNPQAGSVTTATSLDFPALSWLRLSAEFGSLRKNAMFVPHYNLNANSIIYALNGRALIQVVNCNGERVFDGELQEGRVLIVPQNFVVAARSQSDNFEYVSFKTNDTPMIGTLAGANSLLNALPEEVIQHTFNLKSQQARQIKNNNPFKFLVPPQESQKRAVA
UniProt: P04776 IUIS: Gly m 6Explore peptide targets for mass spectrometry by adjusting the selection criteria below. Results from empirical and computational prediction tools have been aggregated for convenience.
1 | Peptide | 2 | Exp.3 | ESP4 | CONSeQ5 |
---|---|---|---|---|---|
K | LVFSLCFLLFSGCCFAFSSR | E | 0 | 0.199 | 0.10232 |
R | EQPQQNECQIQK | L | 3 | 0.331 | 0.38698 |
K | LNALKPDNR | I | 3 | 0.232 | 0.39334 |
R | IESEGGLIETWNPNNKPFQCAGVALSR | C | 3 | 0.457 | 0.16818 |
R | RPSYTNGPQEIYIQQGK | G | 4 | 0.383 | 0.39378 |
K | GIFGMIYPGCPSTFEEPQQPQQR | G | 5 | 0.823 | 0.2694 |
R | GQSSRPQDR | H | 0 | 0.227 | 0.1055 |
R | FYLAGNQEQEFLK | Y | 5 | 0.605 | 0.37508 |
K | YQQEQGGHQSQK | G | 3 | 0.36 | 0.22192 |
K | HQQEEENEGGSILSGFTLEFLEHAFSVDK | Q | 5 | 0.481 | 0.15014 |
K | NLQGENEGEDK | G | 3 | 0.337 | 0.13854 |
K | GAIVTVK | G | 1 | 0.22 | 0.53132 |
R | NGIDETICTMR | L | 0 | 0.399 | 0.30478 |
R | LSAEFGSLR | K | 7 | 0.476 | 0.66494 |
K | NAMFVPHYNLNANSIIYALNGR | A | 3 | 0.516 | 0.07818 |
R | ALIQVVNCNGER | V | 3 | 0.615 | 0.6837 |
R | VFDGELQEGR | V | 9 | 0.538 | 0.736 |
R | VLIVPQNFVVAAR | S | 8 | 0.641 | 0.2974 |
R | SQSDNFEYVSFK | T | 8 | 0.626 | 0.4661 |
K | FLVPPQESQK | R | 1 | 0.473 | 0.68128 |
K | LVLSLCFLLFSGCFALR | E | 0 | 0.186 | 0.14108 |
R | EQAQQNECQIQK | L | 2 | 0.321 | 0.4056 |
K | LNALKPDNR | I | 3 | 0.232 | 0.39334 |
R | IESEGGFIETWNPNNKPFQCAGVALSR | C | 1 | 0.384 | 0.14994 |
R | SQRPQDR | H | 0 | 0.211 | 0.1078 |
R | FYLAGNQEQEFLK | Y | 5 | 0.605 | 0.37508 |
K | YQQQQQGGSQSQK | G | 2 | 0.376 | 0.29032 |
K | QQEEENEGSNILSGFAPEFLK | E | 4 | 0.715 | 0.33498 |
K | EAFGVNMQIVR | N | 8 | 0.482 | 0.42222 |
R | NLQGENEEEDSGAIVTVK | G | 4 | 0.698 | 0.6282 |
R | VTAPAMR | K | 0 | 0.245 | 0.23516 |
R | KPQQEEDDDDEEEQPQCVETDK | G | 2 | 0.654 | 0.29266 |
R | NGIDETICTMR | L | 0 | 0.399 | 0.30478 |
K | LSAQYGSLR | K | 3 | 0.394 | 0.6995 |
K | NAMFVPHYTLNANSIIYALNGR | A | 4 | 0.504 | 0.05638 |
R | ALVQVVNCNGER | V | 2 | 0.574 | 0.68858 |
R | VFDGELQEGGVLIVPQNFAVAAK | S | 4 | 0.654 | 0.04414 |
K | SQSDNFEYVSFK | T | 8 | 0.626 | 0.4661 |
K | NNNPFSFLVPPQESQR | R | 2 | 0.864 | 0.56882 |
K | LVLSLCFLLFSGCCFAFSFR | E | 0 | 0.15 | 0.11016 |
R | EQPQQNECQIQR | L | 2 | 0.367 | 0.36888 |
R | LNALKPDNR | I | 3 | 0.232 | 0.39334 |
R | IESEGGFIETWNPNNKPFQCAGVALSR | C | 1 | 0.384 | 0.14994 |
K | GQSSRPQDR | H | 0 | 0.227 | 0.1055 |
R | FYLAGNQEQEFLQYQPQK | Q | 3 | 0.644 | 0.26782 |
K | QQGGTQSQK | G | 0 | 0.261 | 0.16086 |
R | QQEEENEGGSILSGFAPEFLEHAFVVDR | Q | 4 | 0.563 | 0.1525 |
K | LQGENEEEEK | G | 0 | 0.248 | 0.21202 |
K | GAIVTVK | G | 1 | 0.22 | 0.53132 |
K | GGLSVISPPTEEQQQRPEEEEKPDCDEK | D | 0 | 0.622 | 0.37682 |
K | HCQSQSR | N | 0 | 0.165 | 0.07498 |
R | NGIDETICTMR | L | 0 | 0.399 | 0.30478 |
K | LSAQFGSLR | K | 4 | 0.464 | 0.67048 |
K | NAMFVPHYNLNANSIIYALNGR | A | 3 | 0.516 | 0.07818 |
R | ALVQVVNCNGER | V | 2 | 0.574 | 0.68858 |
R | VFDGELQEGQVLIVPQNFAVAAR | S | 1 | 0.608 | 0.03558 |
R | SQSDNFEYVSFK | T | 8 | 0.626 | 0.4661 |
K | NNNPFSFLVPPK | E | 2 | 0.767 | 0.53518 |
^ | MGKPFTLSLSSLCLLLLSSACFAISSSK | L | 0 | 0.209 | 0.0828 |
K | LNECQLNNLNALEPDHR | V | 2 | 0.63 | 0.39096 |
R | VESEGGLIQTWNSQHPELK | C | 4 | 0.717 | 0.35252 |
K | CAGVTVSK | L | 3 | 0.242 | 0.32188 |
R | NGLHLPSYSPYPR | M | 3 | 0.684 | 0.35168 |
R | MIIIAQGK | G | 3 | 0.231 | 0.3763 |
K | GALGVAIPGCPETFEEPQEQSNR | R | 0 | 0.861 | 0.50626 |
K | QQLQDSHQK | I | 0 | 0.236 | 0.24112 |
R | VFYLAGNPDIEYPETMQQQQQQK | S | 4 | 0.699 | 0.29392 |
K | QGQHQQEEEEEGGSVLSGFSK | H | 2 | 0.618 | 0.4692 |
K | HFLAQSFNTNEDIAEK | L | 4 | 0.753 | 0.39634 |
K | LQSPDDER | K | 2 | 0.225 | 0.13154 |
K | QIVTVEGGLSVISPK | W | 4 | 0.766 | 0.92768 |
K | WQEQQDEDEDEDEDDEDEQIPSHPPR | R | 3 | 0.478 | 0.31158 |
R | EQDEDEDEDEDKPRPSRPSQGK | R | 0 | 0.317 | 0.24334 |
R | EQDQDQDEDEDEDEDQPR | K | 2 | 0.584 | 0.2822 |
R | NGVEENICTLK | L | 1 | 0.485 | 0.56692 |
K | LHENIARPSR | A | 0 | 0.217 | 0.28564 |
R | ADFYNPK | A | 3 | 0.23 | 0.33692 |
R | ISTLNSLTLPALR | Q | 6 | 0.629 | 0.59184 |
R | QFQLSAQYVVLYK | N | 3 | 0.406 | 0.28524 |
K | NGIYSPHWNLNANSVIYVTR | G | 3 | 0.495 | 0.13076 |
R | VVNCQGNAVFDGELR | R | 3 | 0.565 | 0.6076 |
R | GQLLVVPQNFVVAEQAGEQGFEYIVFK | T | 3 | 0.368 | 0.04948 |
K | THHNAVTSYLK | D | 3 | 0.507 | 0.16722 |
R | AIPSEVLAHSYNLR | Q | 5 | 0.695 | 0.69544 |
R | QSQVSELK | Y | 2 | 0.235 | 0.38848 |
K | YEGNWGPLVNPESQQGSPR | V | 4 | 0.819 | 0.5185 |
^ | MGKPFFTLSLSSLCLLLLSSACFAITSSK | F | 0 | 0.219 | 0.06612 |
K | FNECQLNNLNALEPDHR | V | 2 | 0.622 | 0.33638 |
R | VESEGGLIETWNSQHPELQCAGVTVSK | R | 2 | 0.578 | 0.21822 |
R | NGLHLPSYSPYPQMIIVVQGK | G | 2 | 0.664 | 0.17478 |
K | GAIGFAFPGCPETFEKPQQQSSR | R | 3 | 0.623 | 0.46682 |
R | SQQQLQDSHQK | I | 3 | 0.306 | 0.2469 |
R | VFYLAGNPDIEHPETMQQQQQQK | S | 3 | 0.647 | 0.37258 |
K | QGQHQQQEEEGGSVLSGFSK | H | 2 | 0.606 | 0.48408 |
K | HFLAQSFNTNEDTAEK | L | 3 | 0.729 | 0.50976 |
K | QIVTVEGGLSVISPK | W | 4 | 0.766 | 0.92768 |
K | WQEQEDEDEDEDEEYEQTPSYPPR | R | 2 | 0.475 | 0.318 |
R | NGVEENICTMK | L | 1 | 0.324 | 0.30844 |
K | LHENIARPSR | A | 0 | 0.217 | 0.28564 |
R | ADFYNPK | A | 3 | 0.23 | 0.33692 |
R | ISTLNSLTLPALR | Q | 6 | 0.629 | 0.59184 |
R | QFGLSAQYVVLYR | N | 3 | 0.398 | 0.22462 |
R | NGIYSPHWNLNANSVIYVTR | G | 3 | 0.495 | 0.13076 |
R | VVNCQGNAVFDGELR | R | 3 | 0.565 | 0.6076 |
R | GQLLVVPQNFVVAEQGGEQGLEYVVFK | T | 1 | 0.424 | 0.0625 |
K | THHNAVSSYIK | D | 2 | 0.536 | 0.1664 |
R | AIPSEVLSNSYNLGQSQVR | Q | 1 | 0.678 | 0.19406 |
K | YQGNSGPLVNP | $ | 1 | 0.444 | 0.47664 |
1 Previous amino acid (^ = Start of protein)
2 Next amino acid ($ = End of protein)
3 Exp. = Number of publications in which this peptide has been reported experimentally
4 ESP = ESP Predictor. Fusaro VA, et al. Nat Botechnol 2009; 27(2): 190-198. doi
5 CONSeQ = CONSeQuence. Eyers CE, et al. Mol Cell Proteomics 2011; 10(11). doi
Underline: Peptide occurs within the first 20 amino acids from the start of the protein. Use caution as the protein may contain a cleaved signaling sequence.
Strike-through: Peptide is present in a protein from another allergen species and is thus nonspecific.