Croote, D., Quake, S.R. Food allergen detection by mass spectrometry: the role of systems biology. npj Syst Biol Appl. 2016 Sep 29; 2:16022.
This rose plot enables visualization of proteotypic peptides. Each colored rose petal corresponds to a peptide and is bounded by thin gray petals, which represent tryptic cut sites. The radial magnitude of each peptide corresponds to the number of publications which report it.
Hover over a rose petal with your mouse to see the peptide. Click on a rose petal to see the species specificity of that peptide and add it to your cart.
MAKPILLSIYLFLIVALFNGCLAQSGGRQQQQFGQCQLNRLDALEPTNRIEAEAGVIESWDPNNQQFQCAGVAVVRRTIEPNGLLLPQYSNAPQLVYIARGRGITGVLFPGCPETFEESQRQSQQGQSREFQQDRHQKIRHFREGDIIAFPAGVAHWSYNDGSNPVVAISLLDTNNNANQLDQNPRNFYLAGNPDDEFRPQGQQEYEQHRRQQQRQQRPGEHGQQQRGLGNNVFSGFDADFLADAFNVDTETARRLQSENDHRRSIVRVEGRQLQVIRPRWSREEQEREERKERERERESESERRQSRRGGRDDNGLEETICTLRLRENIGDPSRADIYTEEAGRISTVNSHTLPVLRWLQLSAERGALYSDALYVPHWNLNAHSVVYALRGRAEVQVVDNFGQTVFDDELREGQLLTIPQNFAVVKRARNEGFEWVSFKTNENAMVSPLAGRTSAIRALPEEVLATAFQIPREDARRLKFNRQESTLVRSRPSRSRSSRSERRAEV
UniProt: Q2TPW5 IUIS: Jug r 4Explore peptide targets for mass spectrometry by adjusting the selection criteria below. Results from empirical and computational prediction tools have been aggregated for convenience.
| 1 | Peptide | 2 | Exp.3 | ESP4 | CONSeQ5 |
|---|---|---|---|---|---|
| ^ | MAKPILLSIYLFLIVALFNGCLAQSGGR | Q | 0 | 0.192 | 0.04794 |
| R | QQQQFGQCQLNR | L | 0 | 0.418 | 0.37494 |
| R | LDALEPTNR | I | 2 | 0.481 | 0.84376 |
| R | IEAEAGVIESWDPNNQQFQCAGVAVVR | R | 0 | 0.389 | 0.0816 |
| R | TIEPNGLLLPQYSNAPQLVYIAR | G | 0 | 0.767 | 0.06156 |
| R | GITGVLFPGCPETFEESQR | Q | 0 | 0.848 | 0.22976 |
| R | QSQQGQSR | E | 0 | 0.235 | 0.17136 |
| R | NFYLAGNPDDEFRPQGQQEYEQHR | R | 0 | 0.436 | 0.38304 |
| R | QQRPGEHGQQQR | G | 0 | 0.189 | 0.22354 |
| R | GLGNNVFSGFDADFLADAFNVDTETAR | R | 0 | 0.411 | 0.0563 |
| R | LQSENDHR | R | 0 | 0.279 | 0.13924 |
| R | QLQVIRPR | W | 0 | 0.224 | 0.43562 |
| R | DDNGLEETICTLR | L | 0 | 0.685 | 0.59636 |
| R | ENIGDPSR | A | 0 | 0.19 | 0.17608 |
| R | ADIYTEEAGR | I | 1 | 0.416 | 0.77404 |
| R | ISTVNSHTLPVLR | W | 0 | 0.725 | 0.67902 |
| R | WLQLSAER | G | 0 | 0.304 | 0.40794 |
| R | GALYSDALYVPHWNLNAHSVVYALR | G | 0 | 0.384 | 0.03904 |
| R | AEVQVVDNFGQTVFDDELR | E | 0 | 0.61 | 0.09684 |
| R | EGQLLTIPQNFAVVK | R | 0 | 0.779 | 0.69952 |
| R | NEGFEWVSFK | T | 0 | 0.498 | 0.27626 |
| K | TNENAMVSPLAGR | T | 0 | 0.669 | 0.95078 |
| R | ALPEEVLATAFQIPR | E | 0 | 0.894 | 0.7228 |
| R | QESTLVR | S | 0 | 0.26 | 0.2324 |
1 Previous amino acid (^ = Start of protein)
2 Next amino acid ($ = End of protein)
3 Exp. = Number of publications in which this peptide has been reported experimentally
4 ESP = ESP Predictor. Fusaro VA, et al. Nat Botechnol 2009; 27(2): 190-198. doi
5 CONSeQ = CONSeQuence. Eyers CE, et al. Mol Cell Proteomics 2011; 10(11). doi
Underline: Peptide occurs within the first 20 amino acids from the start of the protein. Use caution as the protein may contain a cleaved signaling sequence.
Strike-through: Peptide is present in a protein from another allergen species and is thus nonspecific.